Irwin made his British Superbikes debut in the first of two spells with PBM Ducati in 2016, and managed 19 wins and 23 podiums over six seasons, narrowly missing out on the 2023 Championship win by just half a point to Tommy Bridewell.
He had finished on the podium in four of the first five races of the 2025 season but missed two rounds after his accident and was replaced by 2019 BSB champion Scott Redding.
The 11-time North West 200 race winner responded to the PBM statement with a video posted on X, external.
“Upon reading the statement I want to reiterate that I have been declared orthopedically fit and have passed all the stage one single leg examinations and I have been returned 100% to full duties of riding bikes in the last seven days,” he said.
“Training has been as normal the past week, but I do want to go on record and thank PBM for all the success we achieved together, all their efforts, their time and their support shown to me and my family I wish them all the best for the future.”
Yamaha team owner David Williams added he was “excited” to welcome Irwin.
“Between him and Kyle, we believe we have the strongest pairing on the current grid and are entering the second half of the British Superbike Championship season with a stronger sense of optimism than ever.”